STORE AT 2-8°C For Research use only

Not for use in diagnosis procedures.

Origin: Synthetic generic Chromogenic substrate, highly purified and stabilized.

Specificity: Recommended substrate for Activated Protein C.

Presentation: Vial containing 25 mg of BIOPHEN CS-21(66), lyophilised in presence of Mannitol as a bulking agent.

Reconstitution: According to the research protocol used, the BIOPHEN CS-21(66) chromogenic substrate can be restored with variable volumes of distilled water; for example 5 mL can be used for a substrate concentration of 5 mg/mL, or 20 mL for a substrate concentration of 1.25 mg/mL..

Peptide sequence: p-Glu-Pro-Arg-pNa. HCl

Chemical structure: C22H30N6O6, HCl

Molarity: ≈50 μmol/vial

Purity grade: > 95%.

Molecular weight: 502.5.

Free pNA content (measured on substrate at 2.5g/L): OD405nm ≤ 0.30

Use:

All research studies and protocols where a source of chromogenic substrate for Activated Protein C is required. This kit is for research use only and should not be used for patient diagnosis or treatment.

Respective reactivities:

APC

FXa

Plasmin

Kallicrein

Thrombin

100

7

85

150

125

Assay conditions must be established for making the substrate totally specific for activated protein C.

Stability:

Restored : - 7 days at room temperature - 3 months at 2-8 °C - Do not freeze.

Lyophilized : Until the expiration date printed on the vial.